The exhibition features a mural painting by Hopi artists Michael Kabotie and Delbridge Honanie displayed for the first time outside of Arizona and the Museum of Northern Arizona.

The impressive work spans nearly five feet tall and forty-eight feet in length, with six distinct but interconnected panels. Journey of the Human Spirit narrates the history of the Hopi people, from the mythic emergence, through the arrival of Europeans, to the rebirth of Hopi traditions in the information age. The contemporary mural was inspired by figural wall paintings created prior to European contact.

The mural will be complemented by ancient to contemporary objects from the DMA's collection, including an ancestral Sikyatki Polychrome bowl with flower design and a modern kachina (katsina) doll of Palhik Mana, among works by other contemporary Hopi artists.