The first exposition entitled “Exhibition of invertebrate animals” was set up in 1955. The exhibited specimens included sponges, cnidarians, worms, mollusks, arthropods, and echinoids. The exhibition contained mainly materials from the former French college.

The permanent exposition of the museum was opened in 1960, further enriched with Bulgarian materials found mainly in the vicinities of Plovdiv. The exposition in “Invertebrates” Hall was entirely renovated, exhibiting specimens of almost all invertebrate species.

The central showcase with exotic mollusks (clams, snails, corals, sponges, etc.) taken from the Caribbean Sea was set up in 1974. This is one of the richest collections in Europe and the only one of its kind in Bulgaria. In 1985, due to the availability of a rich collection of exotic mollusks, a new hall called “Sea bottom” was opened as part of this section.

In 1988, the entire exposition was renovated in accordance with a new thematic plan.

It is presented the 3D vision of the hall. The new exhibition will include complete systematic collection of invertebrates in their typical habitats. Also there will be two modules with insects: bee hives and ant.